Drug Dosing Adjustment During Ramadhan

Adan in healthy volunteers showed a significant The patients took their drugs at 8 am outside Ramadan decrease in the amount of drug absorbed for the 8 pm and at the break of fasting 7-8 pm during Ramadan. Changing the time the number of doses interval between dosages without consulting a doctor may be.

Ramadan Patient Assessment Flowchart Hcp Healthcare Professional Download Scientific Diagram

During Ramadan change the timing of the once daily dose of sulphonylurea from the usual morning dose to the evening at Iftar and reduce from its actual dose to 75 of the total dosage at start and then adjust according to the glycemic control the dosage is not constant and change it accordingly.

. 12 However clinical practice suggests that drugs are taken once or twice daily such as NOACs do not require an adjustment. Intake two hours after Iftar. Duration between each meal consumed during Ramadan the intake of medicines is therefore not rational.

Medication adjustments can include. Although this class of drugs are safe to use in T2DM patients during Ramadan due to their lower risk of hypoglycemia not many studies are available to confirm the same. 75 for sulfonylureas 75 for glargine 75 for premixed insulin 7030 in two doses and 75 for regular insulin.

13 Recent research from Australia found that pharmacists are generally willing to counsel patients during Ramadan but tend to perceive that there is little need for intervention unless directly asked. Again as emphasized earlier the overall dosage of medications especially that of insulin must be adjusted in conjunction with the weight loss or gain that may occur during Ramadan. Almost 40 of the GPs responded incorrectly to the questions regarding drug dosage adjustment in people with diabetes during Ramadan.

Pharmacists can help patients adjust their medications during Ramadan to ensure safe and effective therapy while fasting. Hypoglycemia occurred at a lower rate than pre-Ramadan values in groups C and D. Several factors might alter the phar-macokinetics and pharmacodynamics of medica - tions consumed during the month of Ramadan3 For examples some patients alter the use of med - ications and their form whereas others alter the intake pattern.

Unlike other classes of drugs dose adjustment is not required with pioglitazone. The administration schedules in macokinetics of theophylline before and during Ram- this study were not the same in the two time periods. However significant weight gain was observed with the pioglitazone group.

75 for sulfonylureas 75 for glargine 75 for premixed insulin. The Low-Ratio Premix Insulin Working Group recently reported a practical outline on how to adjust insulin during the fasting period based on premeal blood glucose levels and the history of hypoglycemia23 This group also recommended a trial fast for three consecutive days before Ramadan to help in detecting hypoglycemia risk and for guiding the self-titration of premix. Pharmacists have a big role to play in helping Muslims adjust medications safely during Ramadan and to identify anyone who cannot safely do so.

With the changes in the mealtime certain drugs dose-schedule have to be altered during Ramadan. A comparative study of the pharmacokinetics of theophylline before and during Ramadan in healthy volunteers showed a significant decrease in the amount of drug absorbed for the 8 pm intake two hours after Iftar compared with the 4 am intake immediately after Sohour. No cases of DKA or NKHS were reported.

During Ramadan drug doses were adjusted as percentages of their pre-Ramadan values. Adjusting the timing of medications throughout the day changing short-acting formulations to longer once- or twice-daily doses or considering alternate routes of administration. Metformin was adjusted to a twice-daily regimen.

There is no randomized evidence on dosing adjustments for Novel oral anticoagulants NOACs with fasting during Ramadan. Illustrative examples and recommendations for adjusting therapy during Ramadan in patients with type 2 diabetes are shown in Table 3. During Ramadan drug doses were adjusted as percentages of their pre-Ramadan values.

Ramadan fasting dose adjustments for metformin in people with T2DM Once-daily dosing Twice-daily dosing Three times daily dosing Prolonged-release metformin No dose modication usually required Take at iftar Morning dose to be taken before suhoor. 6 This result was mainly explained by the changes in the circadian variations of the gastric pH. For patients on twice a day dosage regimen reduce the morning dose to 75.

Clinical data on its use during Ramadan. A comparative study of the pharmacokinetics of theophylline before and during Ramadan in healthy volunteers showed a significant decrease in the amount of drug absorbed for the 8 pm intake two hours after Iftar compared with the 4 am intake immediately after Sohour6 This result was mainly explained by the changes in the circadian variations of the. One study has evaluated the effects of Figure 2.

However more than 80 responded in agreement regarding alteration in medication timings.

Algorithm For Premixed Insulin Titration During Ramadan Download Scientific Diagram

Medicines Healthcare And The Holy Month Of Ramadan British Islamic Medical Association

Diabetes And Ramadan Practical Guidelines By International Diabetes Federation Issuu

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